Waynesboro is home to the Renfrew Museum and Park, an historical museum depicting 18th century farm life, named after two young sisters who supposedly died there in 1764 in an Indian attack.

During the American Civil War, Waynesboro, a strongly pro-Union town, played a part in the Gettysburg Campaign in June and July 1863. In the week before the Battle of Gettysburg, Confederate Major General Jubal Early's division of Lieutenant General Richard S. Ewell's corps of the Army of Northern Virginia passed through the community on its way northward. After the battle, General Robert E. Lee rode through the border community with his retreating forces.

Panorama by Alan Chaffee Photography